It just gained FPU and AM5x86 support, so if you ever wanted to try Quake on (simulated) 486 hardware the lazy way without having to build a whole 486, you can.

Be aware you'll need a very powerful computer to emulate the later 486 CPUs, and by powerful I mean 3ghz+ AMD or Core isomething
This isn't really a subsitute for DOSBox, but it's one of the only x86 emulators I know with a choice for a target CPU and BIOS (yes, it emulates the BIOS as well, and it can also have the option to simulate the speed of the ISA bus)
It also can run Windows 95 which DOSBox can't support.